Open one PhD student at the CRBS in the addiction team (Université de Strasbourg-INSERM)
KEY WORDS
addiction, behavior, neuroscience
CITY
Strasbourg
COUNTRY
France
DETAILS OF THE OFFER
Working place: Strasbourg Biomedicine Research Center
Missions:
Our group is a multidisciplinary team and studies the role of G protein coupled receptors, including opioid and orphan receptors, in brain function and disease with an emphasis on reward/aversion processing, addiction and mood disorders. The laboratory develops customized genetic mouse mutants with targeted gene mutations to model psychiatric disorders and manipulate neuronal circuitries, and for drug discovery programs (see Otsu et al. Science, 2019; Bailly et al. 2023 Biological Psychiatry and Welsch et al.2023; Biological Psychiatry).
Mice are characterized using sophisticated behavioral methods, calcium imaging, opto/chemo-genetics and neuroimaging approaches translatable to human research. The PhD student will work on hedonic balanc and habenula. The goal is to map and identify the contribution of habenular neurons expressing opioid receptors in hedonic balance using genetically modified animals combined with calcium imaging and opto/chemo-genetics. This project is financed by the National Institute of Health, USA and ANR, France.
Qualifications:
Master in Neuroscience /Pharmacology or equivalent and/or MD/PhD or PharmD/PhD cursus
Strong interest in mouse behavior and brain circuit analysis
High motivation to conceptualize and develop a research project
Excellent writing and communication skills
Ability to work in a team
Preferred Qualifications: Experience or interest in pre-clinical neuroscience research in the field of mental health
