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itneuro





Postdoctoral fellowship in Neurobiology and animal behavior


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  • Type d'offre : CDD
  • Ville : Bordeaux (France)
  • Statut : Recrutement en cours
Date d'arrivée à l'ITMO : Jeudi 21 Octobre 2021

Postdoctoral fellowship in Neurobiology and animal behavior

Imprimer l'offre

Ville

BORDEAUX

Pays

FRANCE

Texte de l'offre

The team « Nutripsy » at the Nutrineuro lab INRAE UMR1286 in Bordeaux University, is seeking for a highly motivated young researcher for a 18-months postdoctoral contract to work on the FRM-funded project " Combined effects of early life stress and diet-induced obesity on depressive morbidity: characterization and mechanisms. "

The aim of this project is to assess the interaction of early life adversity and adult obesity-driven inflammation on depressive morbidity. The recruted post-doc will be involved in a preclinical workpackage of the project that combines viral-gene transfer methods in mice to specifically alter key enzymes of GCH1/BH4 pathway selectively in the DA system so as to establish causal mechanistic links between this molecular pathway, DA function and dimensions of depressive-like behavior. The efficacy of such manipulations in rescuing alterations in DA transmission and behavioral deficits will be assessed in our models of early life stress (maternal separation combined with unpredictable chronic mild stress in dams) and/or obesogenic diet exposure.

Expected background and skills: animal behavior (perinatal nutrition ; early-life stress ; anxiety, depression models ; expertise in instrumental behaviors will be a plus); stereotaxic surgery and classical neuroscience-related methods such as neuroanatomy, histology...; classical molecular and cellular biology technics (RT-/PCR, western blot, immunohistochemistry).

Applications in a single pdf file should include:
 complete CV, including the list of publications
 research interest statement (2 pages)
 letters of recommendation

Expected Starting date: April 2022

Date de fin de publication :

MAI 2022

Type d'emploi

Post-Doctorat - Post-Doctoral position

Type de contrat

CDD

Date limite de candidature

APRIL 22

Date début de fonction

APRIL 22

 

Information contact

Professeure Muriel Darnaudéry université de Bordeaux
lab NutriNeurO- UMR INRAE 1286
146, rue Léo Saignat, Case 34 33076 Bordeaux cedex, FRANCE
muriel.darnaudery@u-bordeaux.fr

 

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