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Offre n°276 (Ref: AAP3-JF14-CNRS) - Tenure Eligible Investigator: Physiology and Neuroendocrinology


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  • Type d'offre : grant
  • Ville : Dijon (France)
  • Statut : investigator
Date d'arrivée à l'ITMO : Mardi 04 Septembre 2018

Tenure Eligible Investigator

Physiology and Neuroen

 

 

Job description 

The University Bourgogne Franche-Comté (UBFC) is recruiting a tenure eligible investigator in the field of Physiology and Neuroendocrinology, specifically in the laboratory Centre des Sciences du Goût et de l’Alimentation (https://www2.dijon.inra.fr/csga/) located in Dijon (France) and jointly operated by CNRS (French National Scientific Research Centre). This position is supported by the French “Investissements d’Avenir” program, project ISITE-BFC. 

We encourage applications of outstanding scientists investigating this field of research owning a PhD degree, featuring at least three years of postdoctoral experience; a substantive record of publications and the potential to develop an independent research program.

The successful applicant will be provided a 450 k¤ grant (including her/his salary and research budget) for a period of three years. The salary will be negotiated on the basis of education and experience. It integrates a benefit package including retirement, health insurance, annual and sick leave.

The tenure eligible position will be provided by CNRS (according to its own recruitment procedure) during the tenure probation period. During the same period, the successful candidate will be committed to apply for an European Research Council (ERC) grant.

We invite the interested candidates to follow the link http://www.ubfc.fr/wp-content/uploads/2016/07/Application-form_Tenure_Track_-Junior-ISITE-BFC.docx to download the form to be filled and returned by email using the "Apply for this job" button.

UBFC and CNRS are equal opportunity employers.

 

The recent evolution of the scientific research in physiology and neuroscience brings new perspectives concerning the study of eating behavior. The development of modern tools in neuroscience makes now possible not only very precise investigations of the brain functioning but also connection with behavioral correlates. These technological advances allow the identification of brain cells involved in a particular eating behavior (cell-specific approach), the mapping of the underlying neuronal network (nerve tracing), and determination of the function of a specific neuronal population on feeding behavior (optogenetics and pharmacogenetics). In situ microscopy and in vivo calcium imaging also show great potential for real-time visualization of the activity of a neural network during a behavioral task. At the same time, sophisticated analyses of eating behavior are now possible thanks to efficient observation systems placed close to the animals. Hunger, motivation, foraging, decision making, choice, chewing, swallowing, and satiety can be studied specifically. The future directions of research in the field therefore aim at linking the hyperspecialization of neurons and the complexity of eating behavior by the joint use of these modern approaches to obtain a new and complete vision of a system.

The research scientist will use modern neuroscience tools, in combination with accurate behavioral analyses and brain imaging to decipher functioning of brain feeding circuits in rodents. He/she will increase our knowledge about intimate brain mechanisms involved in appetite and metabolism both in physiological conditions, at the meal scale, and in animal models of eating disorders.

 

About the hosting research team

The researcher will join a team which studies the plasticity of brain circuits that control food intake. According to models, the team investigate different aspects of neural plasticity (neuroglial interaction, synaptogenesis, neuronal activity) in response to changes in the prandial state and during disease (obesity and related disorders, anorexia), and to determine the role of this process in eating behavior.

 

Desired skills and experience

Targeted profile
  • PhD in Physiology or Neuroscience
  • Experience in animal surgery, stereotaxy, microdissection, genetic tools and models
  • Histology, microscopy, 3D brain imaging (cell interaction)
  • Pharmacogenetics and/or In situ calcium imaging and/or optogenetic electrophysiology
  • Good skills in data analysis and visualization 

For further information: https://www2.dijon.inra.fr/csga/site_engl/equipe_15.php or contact Dr Alexandre Benani (alexandre.benani@u-bourgogne.fr)

Areas of Research
  • Electrophysiology
  • Cellular Neuroscience
  • Neuroscience

 

Discover more

 

 

Contact

Alexandre Benani : alexandre.benani@u-bourgogne.fr



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