Post doc - depression, new therapy

Ville

Paris

Pays

France

Texte de l'offre

In the framework of a short collaboration with a start-up studio, the team is recruiting a post-doc researcher who will take in charge, under the supervision of the SNRG team leaders (https://www.ibps.sorbonne-universite.fr/fr/Recherche/umr-8246/signalisation-neuronale-et-regulations-geniques), series of experiments aimed at determining the antidepressant properties of new molecules in preclinical models of depression in mice. She/he will have in charge all the behavioral experiments, their quantitative measurements and their interpretation. He/she will perform immunohistochemical and FISH (fluorescent In Situ Hybridization) experiments on post-mortem brain sections, as well as Q-RT-PCR assays on blood extracts to study biomarkers of depression and their regulation by antidepressant treatments.

The areas of expertise within the team cover many fields: from cellular and molecular studies to studies of complex motor and cognitive behavior in mice. Our skills also include expertise in histology and cellular imaging on post-mortem brain sections in humans.

The selected candidate will have
Solid theoretical and practical knowledge of animal behavior (level 1 animal experimentation certificate)
Theoretical and practical knowledge of immunohistochemistry and imaging on post-mortem brain sections
Practical knowledge of image acquisition techniques using confocal microscopy
Practical knowledge of software dedicated to imaging fields (Metamorph, ImageJ FlowJo...)
Interpersonal skills: listening skills and adaptability to interact with team members and the scientific consortium.
Theoretical and practical knowledge in biology
Theoretical and practical knowledge in statistics

Although the CDD period is short (7 months) a possible extension may be considered depending on the results obtained

constraints include: Some weekends for behavioral studies.

Date de fin de publication :

26/09/2022

Type d'emploi

Post-Doctorat - Post-Doctoral position

Type de contrat

CDD

Rémunération brut mensuelles

between 2743 and 3896 euros, depending on the experience

Date limite de candidature

15/09/2022

Date début de fonction

17/10/2022

Information contact

Dr Jocelyne Caboche : jocelyne.caboche@upmc.fr