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Postdoctoral position in neurophysiology


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  • Type d'offre : CDD
  • Ville : Paris (France)
  • Statut : Recrutement en cours
Date d'arrivée à l'ITMO : Vendredi 21 Mai 2021

Postdoctoral position in neurophysiology

Ville

Paris

Pays

France

Texte de l'offre

We seek to hire a highly motivated young postdoctoral fellow to work in electrophysiology in brain slices and in vivo. A background in behavior as well as experience with transgenic mice and glial cells would be appreciated, but not required. The post-doc candidate will integrate our team located in the new Institut of Psychiatry and Neuroscience of Paris (IPNP) inside Sainte-Anne Hospital, a highly stimulating environment. He/she will investigate how neuron-oligodendroglia interactions drive neuronal circuit function and mouse behavior.
Interestingly, cortical GABAergic interneurons and some populations of oligodendroglia are born from the same embryonic origin, migrate through similar routes and interact through synaptic contacts once in place in the cortex. In addition, interneurons and oligodendroglia are demised in a large proportion by programmed cell death at early postnatal stages (Orduz et al., 2019). However, the functional relevance of interneuron-oligodendroglia interactions and their developmental cell death are still poorly understood. The project will explore the impact of the aforementioned common features of these cell types on cognitive processes and neurodevelopmental disorders by using a multidisciplinary approach ex vivo and in vivo in different transgenic mice.

Five selected publications of the team:
 Benamer N et al. (2020) Nat Commun 11:5151
 Orduz D et al. (2019) Nat Commun 10:4249
 Ortiz FC et al. (2019) JCI Insight 4(9):e123434
 Wake H et al. (2015) Nat Commun 6:7844
 Orduz D et al. (2015) eLife 4:e06953
Website: https://ipnp.paris5.inserm.fr/research/teams-and-projects/19-https://ipnp.paris5.inserm.fr/research/teams-and-projects/19-equipe-angulo-angulo

Interested candidates should send their CV, a motivation letter including research interests and letters or names of 2 referees to: maria-cecilia.angulo@parisdescartes.fr

Date de fin de publication :

31/12/2021

Type d'emploi

Post-Doctorat - Post-Doctoral position

Type de contrat

CDD INSERM

Rémunération brut mensuelles

acoording to INSERM grids

Date limite de candidature

31/12/2021

Date début de fonction

possible from september 2021

Information contact

Maria Cecilia Angulo: maria-cecilia.angulo@parisdescartes.fr
Team: Neuron-oligodendroglia interactions in myelination and myelin repair
Insitute of Psychiatry and Neuroscience of Paris (IPNP); INSERM U1266, Paris, France

 

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